United States securities and exchange commission logo May 19, 2022 Jay Venkatesan, M.D. President and Chief Executive Officer Angion Biomedica Corp. 51 Charles Lindbergh Boulevard Uniondale, New York 11553 Re: Angion Biomedica Corp. Registration Statement on Form S-3 Filed May 16, 2022 File No. 333-264994 Dear Mr. Venkatesan: This is to advise you that we have not reviewed and will not review your registration statement. Please refer to Rules 460 and 461 regarding requests for acceleration. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Please contact Abby Adams at (202) 551-6902 with any questions. Sincerely, Division of Corporation Finance Office of Life Sciences cc: Kenneth L. Guernsey, Esq.